New Year, new mutations. We hope everyone has a very safe and enjoyable holiday period and for those who are spending their leave from work gaming, here are some mutations to play with. There is some nice synergy with Fire Ennead and Void Dynasty, so you won’t need to be swapping gems for boss fights if you choose to do the higher mutations there. Some nice artifacts, especially the Butcher, which places Dynasty as my number 1 pick for this week.

There are three levels of Mutation, as well as Story mode, for each Expedition.

  • M1 requires 650 gear score and is relatively easy, introducing the mechanics of the mutation type at a reduced level of damage.
  • M2 is a little harder and requires 675 gear score, with increased scaling and the addition of the Promotion challenges. It is still quite simple to do with an experienced group and is probably the most efficient mode, with improved loot for little effort.
  • M3 requires 695+ gear score and optimised perks, gems and buffs. It is considerably more challenging than M2, both with increased scaling and the addition of the mutation Curse as well as the Promotion.

Note: Elemental damage gems in your weapons are simply recommendations based on the elements your enemies are weakest to. Your playstyle may suit non-elemental gems better and you are encouraged to continue using those if so.

Expedition specific

General buffs

Mutation specific

Artifact: The Butcher Sword

The Dynasty Shipyard we explored on our way to level 60 has become a lot more difficult, and more rewarding. Healers, in particular, can get some very nice looking loot here, and as a mutation it’s all at that higher level. 

The two boss fights in Dynasty can be tricky, and it can be good to bring an off-tank to the dog fight in order to keep them separated. Empress Zhou Taiyang is as challenging as ever, so remember to stay away from her pink magic, stack the pylons against the back wall and run back to the door to fight.

Mutation: Eternal

It’s all purple in Dynasty this week, with the Eternal mutation transforming the enemies to Void damage, so go with the theme and protect yourself with AmethystsParanoia is particularly annoying, with stacks building up as you hit the enemy. When you reach 4 stacks, a purple pool appears at your feet, dealing 40-70% damage. This is easily dodged as an individual, but when the melee are crowded together, you can end up with some big spikes of pain. It might be an opportunity to try a ranged DPS team for a change, with the tank holding aggro and 3 bow users shooting from afar. Creeping enemies Empower their friends when they die and Oblivion enemies use a life leech that heals them when they hit you. 

At M1 level, everything is a bit easier, so you will be fine with Opals rather than Amethysts, and may not need to use Ward potions or Coatings.

M2 - Barbaric

At M2, some enemies start being Barbarically buffed. Shattering is annoying for your tank, dealing 40-75% increased stamina damage! It might even be worth stacking more of the stamina perks to keep up. Watch out for those large Enraged enemies, who deal 50% more damage once they get 20 stacks of Fury.

M3 - Censored

In M3, players are Censored with silence. Using abilities causes a meter to build up and when it is full, silence is cast on each member of the group where they are standing. Abilities cannot be used inside the silence zone and when it expires, it detonates with a massive 65% max health damage. So it’s pretty important to keep an eye on the meter and make sure that silence zones are strategically placed. You can deliberately set off Silence before big fights, and in boss battle arenas you can clump to stack the Silence and reduce the area impacted. While silence is active, natural mana regen is turned off, however you can get 25 mana per 0.75 seconds by standing in the silence. Just don’t be in there when it explodes!

Expedition specific

General buffs

Mutation specific

Artifact: The Wall Tower Shield

The Ennead has more bosses than any other organisation, with three major boss fights and two bosses in the final battle. This brings us to a total of four big bosses. And don’t forget, you have to defeat the last two twice. This expedition also starts out with Ancient enemies, but with a Brimstone flavour, so if you’re getting toasted, you can consider adding some Fire protection. 

The first boss you encounter is Godling Khepri Supernal, a giant scarab beetle. You need to use the architecture of the room to avoid his laser beam, by running around to the other side of the pillar once he starts casting. As long as the group works together, this is a pretty easy fight.

After getting through the twists and turns of the first maze-like section, you will use three Azoth staves to burst a Corruption bubble and encounter a series of Corrupted enemies. This culminates in the second boss fight, with General Crassus. He goes through three phases and summons a lot of adds, so it’s worth having dedicated DPS keeping them under control.

The final boss fight is a doozy. It starts with Anpu, aka Big Guy, who has some nasty elemental attacks, reaching out with ranged spikes and causing an AOE spin, as well as smacking down like a regular brute. The one attack you can control to some degree is his charge, which is usually targeted at the furthest player. If they keep a pillar between Anpu and themselves, he will bonk his head and stop his charge. Make sure you don’t stand in the trail he leaves when he charges, as it does major damage.

Once you knock Anpu over, his little buddy, Heru (aka Small Guy), turns up. He is infinitely more annoying, because he requires the whole team to work together. When he enters his levitation stage in the middle of the arena, four players need to be at each of the floating pillars and use their azoth staves, while suffering massive tick damage. It’s worth drinking a regen pot just before using your staff, to keep the ticks under control. He also stuns and creates damage zones, so be careful.

The real fun starts once Heru goes down, as at this point they both get up and the place becomes chaotic. If you don’t kill them both within 30 seconds of each other, the other one respawns, so one strategy is to get Small Guy down to almost dead, then focus on Big Guy, then when he is almost dead, take them both down. Just careful of Small Guy going into his levitation phase while you’re trying to fight Big Guy, it’s good to have a lot of DPS here to get this fight over and done with. 

Mutation: Hellfire

Burn baby burn, this rotation it’s Fire. We start with the basic Hellfire. Look at the enemies’ nameplates to see whether they are Explosive, and be sure to position yourself well away from edges when they die, to avoid being blown over. Fiery enemies apply Burn, giving you a Fire DOT, so it’s worth drinking some Desert Sunrise before you start. Ignited enemies deal 50% of their damage as Fire, so slot Rubies in your armour and wear a Flame Protection amulet to get your Fire resistance up. Enemies with Enflamed can cast a Burn zone on the ground, so watch your positioning.

At M1 level, everything is a bit easier, so you will be fine with Opals rather than Rubies, and may not need to use Ward potions or Coatings.

M2 - Savage

When you get to M2, Festering enemies start to appear, dealing disease against you so your incoming healing will be reduced. Remember, debuffs can be Purified in a number of ways. Slicer enemies also turn up, adding 30% base Void damage, so think about diversifying your protective gems in this mutation.

M3 - Fiendish

The first of our M3 curses is Weary, which slows down player movement as well as increasing damage taken by 20%. This is on a timer and while you’re meant to be able to delay it by using abilities, it’s been glitchy in game so don’t rely on that.

The other curse is Blood Offering. Using abilities causes a 4.5% Fire DoT, which can stack up to 3 times, however while under the influence of Offering players also get a 25% life leech. So as long as you’re doing damage, this curse has little effect. The main person it impacts is the healer, so they may need to focus on healing themselves. Drinking some Desert Sunrise before you start the expedition should help reduce the effect.

Expedition specific

General buffs

Artifact: Spark of Mjölnir War Hammer

It’s The Lazurus Instrumentality week, everyone’s favorite place to be. As always, Ancient enemies require ancient solutions and this means Hammers! Crush those bones down, but don’t forget the utility of your secondary weapons. Every good mutation team benefits from a Spear with Perforate and a Great Axe with Grav Well to keep things running smoothly. Or any other way you can think of to weaken those enemies and buff up your friends.

You might want to consider Topaz for your weapons, as it converts some of your damage to Lightning, which is strong against Ancients, or you might choose to slot an Emerald for those large numbers in Chardis’ final down phase. Add an Ancient Coating, Infused if you can afford it, and a Honing stone to maximise damage. Chug down an Ancient Ward potion before getting started for some extra protection. Remember to eat an attribute food of your choice and take your Topaz if you need to collect some gypsum.

Mutation: Overgrown

Overgrown means those mobs are going to be healing one another, which really should be a privilege exclusive to us. Compost mobs drop a healing circle that works like a Sacred Ground for them and looks a bit like one too. This is one of the rare times that disease perks are useful in PVE, so pull out your Hatchet with Infected Throw, or slot a weapon with Plagued Strikes or Plagued Crits. Your Bile Bomb heartrune will also spread disease around, so vomit away to your heart’s content.

Toxic mobs spawn THE most annoyingly friendly little green blob that follows you around, does damage over time that increases at the higher mutations, and casts an area root. We just love not being able to move and getting damaged at the same time! Best bet is to try and stay out of its way. If you get stuck, it might be worth it to have Nature Absorption potions slotted and chug one down. Arboreal enemies are dealing 50% of damage as Nature, and Bramble enemies deal 20-40% base damage as Nature, so Amber slotted in your gear will protect you.

At M1 level, everything is a bit easier, so you will be fine with Opals rather than Ambers, and may not need to use Ward potions or Coatings.

M2 - Oppressive

Once we reach M2, we start seeing Mage Hunters, who drain mana when hit, so healers need to make sure their mana potions are slotted. Suppressor enemies cast a silence zone in which no abilities can be used, but at least it doesn’t have the explosion at the end.

M3 - Dessicated

The Curse of the Overgrown Instrumentality is Desiccated, which is your basic dip and nae-nae. When a player gets a Nature ring around them, they need to dip all team members in order to remove their Shrivel. But make sure they nae-nae away before the timer ends to avoid spiking others with a chain Nature for 50% of their max health. If you’re unlucky enough to be left shrivelled, damage and healing will be reduced by 50% until the debuff wears off.

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